GOD AKA Chuck Shurley in the Supernatural Universe is the creator of everything. He along with his sister Amara are primordial beings who are responsible for the universe and they maintain the balance necessary for the functioning of it. During the apocalypse, he was gone missing. Chuck would return from the sidelines after his sister Amara came calling and causing all sorts of destruction.
Similar to SPN, God in the Lucifer universe is the creator of everything. He is also responsible for the existence of Chloe Decker who was born as a result of Amenadiel’s blessing, carrying a divine grace. God knew beforehand how things are going to play out. He appeared on earth after a long time where he reconnected with Lucifer, telling him that he plans on retiring.
In the SPN Universe, Michael is the first angel created by Chuck, he is also the most powerful archangel. It was Michael who fought against Lucifer and helped in banishing his brother. The Winchester bloodline can house Michael, serve as his vessel. Even though it was destined that Dean would serve as the vessel of Michael in the apocalypse battle, but after Dean’s denial, Michael took over Adam, the son of John Winchester. Michael was trapped in the cage along with Lucifer where he lost his mind. After escaping the cage, he is surprised at Chuck’s betrayal, he aligns himself with the Winchesters. But it was only a ploy to become his father’s favorite son again.
The Michael in the Lucifer Universe isn’t righteous, he is actually manipulating, devious, and a liar who uses people’s fears against them. He served as the main villain of Season 5 of Lucifer. It was Michael who influenced his brother Lucifer in rebelling against God, he has always been jealous of Lucifer. After God announced his retirement, Lucifer and Michael contested to become the next God. While Michael had the support of te majority of his siblings, but Lucifer managed to defeat him in the battle.
Lucifer in Supernatural has served as an antagonist in numerous seasons. He is the archangel who loathed the humanity and was banished from the heaven due to his antics. He would rule the underworld, create the demons who would do his bidding. Sam Winchester is the true Vessel of Lucifer who consented to house the archangel in Season 5 and was supposed to be Adam who was possessed by Michael, but Dean prevented the apocalypse.
Lucifer Morningstar in the show Lucifer is the main protagonist of the story. This Lucifer got bored of his duties of the underworld and decided to take a vacation to earth. He would open a nightclub where he crossed paths with a detective named Chloe Decker who intrigued him, attracting his curiosity, he began working with her and assisting her in solving the crimes. Chloe Decker is the only human on the planet who is immune to Lucifer’s charm.